SYNTHESIS AND CHARACTERIZATION OF TWO 1,2,4-OXADIAZOLE-FURAZAN-BASED NITRATE ESTER COMPOUNDS AS POTENTIAL ENERGETIC PLASTICIZERS

Synthesis and characterization of two 1,2,4-oxadiazole-furazan-based nitrate ester compounds as potential energetic plasticizers

Two novel energetic compounds, 3-nitroxymethyl-5-(4-nitro-furazan-3-yl)-1,2,4-oxadiazole (4) and 3-nitroxymethyl-5-(4-azido-furazan-3-yl)-1,2,4-oxadiazole (5), were synthesized.Both of them were fully characterized, and the structure of 4 was further confirmed by X-ray single crystal diffraction.The thermal behaviors, detonation performances and th

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Palisaded neutrophilic and granulomatous dermatitis following a long-standing monoclonal gammopathy: A case report

Background: Palisaded neutrophilic granulomatous dermatitis is a rare inflammatory dermatosis with possible underlying systemic conditions including rheumatoid arthritis, autoimmune connective tissue disease, and malignancies.Case Summary: We report a case of an 84-year-old man presenting with a 3-week eruption of asymptomatic annular plaques on hi

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A gender-medicine post hoc analysis (MetaGeM) project to test sex differences in previous observational studies in different diseases: methodology

Delia Colombo,1 Gilberto Bellia,1 Donatella Vassellatti,1 Emanuela Zagni,1 Simona Sgarbi,2 Sara Rizzoli21Novartis Farma, Origgio, 2MediData, Modena, ltaly Abstract: Only recently has medical research begun to understand the importance of taking sex into account, recognizing that symptoms and responses to medical treatm

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Laparoscopic retrieval of impacted Dormia basket

For choledocholithiasis, endoscopic management is the first line of treatment.Both Dormia basket and balloon catheter are used to retrieve common Insurance bile duct (CBD) stones.Here we present a case of impaction of the Dormia basket during an endoscopic procedure.The patient was managed through laparoscopic choledochotomy, and the basket was fou

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